The No. 2 Oregon Ducks are favored by nearly 30 points in their Friday night matchup against Purdue in West Lafayette, Indiana.
Will Oregon cover the spread, or will the Boilermakers make it a game one week after pushing Illinois to overtime?
- WATCH: Stream most of this week’s top college football games live for FREE with Fubo (free trial) or with DirecTV Stream (free trial).
Meanwhile, an injury-riddled Oregon State squad plays host to the UNLV Rebels on Saturday night. Can the Beavers, who are 6.5-point underdogs, win at home?
Elsewhere in the Big Ten this week, Michigan travels to Illinois for a top-25 matchup and one-loss Nebraska visits undefeated Indiana.
Check out this week’s college football odds, plus score predictions for select games from the college football coverage team at The Oregonian/OregonLive.
No. 2 Oregon (6-0, 3-0) at Purdue (1-5, 0-3)
Game details: 5 p.m. PT Friday at Ross-Ade Stadium in West Lafayette, Indiana
TV channel and live stream: Fox and Fox Sports Live
Latest line: Oregon by 29.5
Over/under: 60.5
Predictions
Ryan Clarke: Oregon 38, Purdue 7
James Crepea: Oregon 42, Purdue 14
Nick Daschel: Oregon 42, Purdue 31
Aaron Fentress: Oregon 44, Purdue 17
Joe Freeman: Oregon 50, Purdue 13
Sean Meagher: Oregon 48, Purdue 17
Joel Odom: Oregon 45, Purdue 10
Bill Oram: Oregon 42, Purdue 17
UNLV (5-1) at Oregon State (4-2)
Game details: 7 p.m. PT Saturday at Reser Stadium in Corvallis
TV channel and live stream: The CW
Latest line: UNLV by 6.5
Over/under: 59.5
Predictions
Ryan Clarke: UNLV 30, Oregon State 20
James Crepea: UNLV 42, Oregon State 28
Nick Daschel: UNLV 45, Oregon State 35
Aaron Fentress: UNLV 29, Oregon State 26
Joe Freeman: UNLV 33, Oregon State 30
Sean Meagher: UNLV 35, Oregon State 31
Joel Odom: UNLV 44, Oregon State 34
Bill Oram: UNLV 38, OSU 17
Nebraska (5-1, 2-1) at Indiana (6-0, 3-0)
Game details: 9 a.m. PT Saturday at Memorial Stadium in Bloomington, Indiana
TV channel and live stream: Fox and Fox Sports Live
Latest line: Indiana by 6.5
Over/under: 49.5
Predictions
Ryan Clarke: Indiana 31, Nebraska 24
James Crepea: Indiana 35, Nebraska 31
Nick Daschel: Indiana 32, Nebraska 28
Aaron Fentress: Nebraska 32, Indiana 30
Joe Freeman: Indiana 25, Nebraska 20
Sean Meagher: Indiana 38, Nebraska 24
Joel Odom: Indiana 34, Nebraska 30
Bill Oram: Indiana 27, Nebraska 21
Wisconsin (4-2, 2-1) at Northwestern (3-3, 1-2)
Game details: 9 a.m. PT Saturday at Lanny and Sharon Martin Stadium in Evanston, Illinois
TV channel and live stream: Big Ten Network and Fox Sports Live
Latest line: Wisconsin by 7.5
Over/under: 41.5
Predictions
Ryan Clarke: Wisconsin 30, Northwestern 27
James Crepea: Wisconsin 24, Northwestern 21
Nick Daschel: Northwestern 20, Wisconsin 17
Aaron Fentress: Wisconsin 27, Northwestern 23
Joe Freeman: Wisconsin 23, Northwestern 14
Sean Meagher: Wisconsin 27, Northwestern 20
Joel Odom: Wisconsin 30, Northwestern 17
Bill Oram: Northwestern 21, Wisconsin 15
UCLA (1-5, 0-4) at Rutgers (4-2, 1-2)
Game details: 9 a.m. PT Saturday at SHI Stadium in Piscataway, New Jersey
TV channel and live stream: FS1 and Fox Sports Live
Latest line: Rutgers by 5
Over/under: 40.5
Predictions
Ryan Clarke: Rutgers 20, UCLA 17
James Crepea: Rutgers 42, UCLA 21
Nick Daschel: Rutgers 28, UCLA 20
Aaron Fentress: Rutgers 23, UCLA 17
Joe Freeman: Rutgers 24, UCLA 17
Sean Meagher: Rutgers 37, UCLA 10
Joel Odom: Rutgers 31, UCLA 21
Bill Oram: Rutgers 33, UCLA 13
No. 24 Michigan (4-2, 2-1) at No. 22 Illinois (5-1, 2-1)
Game details: 12:30 p.m. PT Saturday at Memorial Stadium in Champaign, Illinois
TV channel and live stream: CBS and Paramount+
Latest line: Michigan by 3.5
Over/under: 44.5
Predictions
Ryan Clarke: Michigan 27, Illinois 24
James Crepea: Illinois 28, Michigan 24
Nick Daschel: Illinois 21, Michigan 20
Aaron Fentress: Illinois 26, Michigan 23
Joe Freeman: Michigan 24, Illinois 20
Sean Meagher: Illinois 24, Michigan 21
Joel Odom: Michigan 27, Illinois 24
Bill Oram: Michigan 38, Illinois 35
Hawaii (2-4) at Washington State (5-1)
Game details: 12:30 p.m. PT Saturday at Martin Stadium in Pullman, Washington
TV channel and live stream: The CW
Latest line: Washington State by 18.5
Over/under: 55.5
Predictions
Ryan Clarke: Washington State 41, Hawaii 14
James Crepea: Washington State 42, Hawaii 21
Nick Daschel: Washington State 24, Hawaii 7
Aaron Fentress: Washington State 37, Hawaii at 27
Joe Freeman: Washington State 42, Hawaii 20
Sean Meagher: Washington State 42, Hawaii 21
Joel Odom: Washington State 41, Hawaii 17
Bill Oram: Washington State 49, Hawaii 6
USC (3-3, 1-3) at Maryland (3-3, 0-3)
Game details: 1 p.m. PT Saturday at SECU Stadium in College Park, Maryland
TV channel and live stream: FS1 and Fox Sports Live
Latest line: USC by 7.5
Over/under: 56.5
Predictions
Ryan Clarke: USC 30, Maryland 10
James Crepea: USC 42, Maryland 21
Nick Daschel: USC 38, Maryland 20
Aaron Fentress: USC 31, Maryland 24
Joe Freeman: USC 33, Maryland 24
Sean Meagher: Maryland 28, USC 24
Joel Odom: USC 34, Maryland 14
Bill Oram: Maryland 28, USC 21
Iowa (4-2, 2-1) at Michigan State (3-3, 1-2)
Game details: 4:30 p.m. PT Saturday at Spartan Stadium in East Lansing, Michigan
TV channel and live stream: NBC and Peacock
Latest line: Iowa by 6
Over/under: 39.5
Predictions
Ryan Clarke: Iowa 21, Michigan State 20
James Crepea: Iowa 31, Michigan State 17
Nick Daschel: Iowa 27, Michigan State 20
Aaron Fentress: Iowa 24, Michigan State 17
Joe Freeman: Iowa 23, Michigan State 17
Sean Meagher: Iowa 31, Michigan State 21
Joel Odom: Iowa 28, Michigan State 10
Bill Oram: Iowa 28, Michigan State 18
